Bioactivity:

NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer. NSC16168 is a specific ERCC1-XPF inhibitor (IC50: 0.42 _M).

CAS nr:

6837-93-0

Purity:

98%

Molecular Weight:

473,5

SMILES:

NC1=C2C(C=C(S(=O)(O)=O)C=C2OS(C3=CC=C(C)C=C3)(=O)=O)=CC(S(O)(=O)=O)=C1

Formula:

C17H15NO9S3

Pathway:

Endocrinology/Hormones

Target:

Estrogen/progestogen Receptor