Bioactivity:

MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 _M) and bovine carboxypeptidase A (CPDA; IC50, 27 _M).

CAS nr:

305335-31-3

Purity:

98%

Molecular Weight:

428,31

SMILES:

CC(C)C[C@H](N[C@@H](Cc1cncn1Cc1cc(Cl)cc(Cl)c1)C(O)=O)C(O)=O

Formula:

C19H23Cl2N3O4

Pathway:

Endocrinology/Hormones

Target:

RAAS