Bioactivity:

CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay).�It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive

CAS nr:

1821387-73-8

Purity:

98%

Molecular Weight:

362,31

SMILES:

CNC1=CC=C(C=C1N2C=C(N=C2)C3=CC=C(C=C3)C(F)(F)F)[N+]([O-])=O

Formula:

C17H13F3N4O2

Pathway:

Immunology/Inflammation

Target:

TLR