Bioactivity:

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is an Mcl-1 inhibitor (IC50: 6.3 _M in FRET assay; Kd: 0.98 _M in SPR assay).

CAS nr:

2143061-82-7

Purity:

98%

Molecular Weight:

672,26

SMILES:

O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5

Formula:

C35H34ClN5O3S2

Pathway:

Apoptosis

Target:

BCL