Bioactivity:

BLZ945 is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs.

CAS nr:

953769-46-5

Purity:

98%

Molecular Weight:

398,48

SMILES:

c1(cc(ccn1)Oc1ccc2nc(sc2c1)N[C@H]1[C@@H](CCCC1)O)C(=O)NC

Formula:

C20H22N4O3S

Pathway:

Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors

Target:

CSF-1R,c-Fms