WYE-132 T6346
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
WYE-125132 (WYE-132) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.
CAS nr:
1144068-46-1
Purity:
98%
Molecular Weight:
519,6
SMILES:
CNC(=O)NC1=CC=C(C=C1)C1=NC2=C(C=NN2C2CCC3(CC2)OCCO3)C(=N1)N1CC2CCC(C1)O2
Formula:
C27H33N7O4
Pathway:
PI3K/Akt/mTOR signaling,Apoptosis
Target:
mTOR,Apoptosis
