Bioactivity:

M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia.�M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin.

CAS nr:

2363165-42-6

Purity:

98%

Molecular Weight:

657,86

SMILES:

O=S(C1=CC=C(N2CC(CN3CCC([C@]4([C@H]5[C@H](OC(NC)=O)CCC5)CN(C)CC6=C4C=CC=C6)CC3)C2)C=C1)(C7=CC=NC=C7)=O

Formula:

C37H47N5O4S

Pathway:

Chromatin/Epigenetic,Chromatin/Epigenetic

Target:

Epigenetic Reader Domain,Histone Methyltransferase