Bioactivity:

PRT062607 (BIIB-057) is a selective inhibitor of Syk (IC50: 1 nM). It displays at least 80-fold selectivity for Syk over other kinases.

CAS nr:

1370261-97-4

Purity:

98%

Molecular Weight:

429,91

SMILES:

Cl.N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(c2)-n2nccn2)n1

Formula:

C19H23N9O�HCl

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,MAPK

Target:

Syk,Syk,Src,Src,MLK