Bioactivity:

DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activity.

CAS nr:

544678-85-5

Purity:

98%

Molecular Weight:

410,42

SMILES:

FC1=C(C=C(C=C1)CNC(C2=CC(C(NCC3=CC=C(C(C)=C3)F)=O)=NC=N2)=O)C

Formula:

C22H20F2N4O2

Pathway:

Proteases/Proteasome

Target:

MMP