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Bioactivity:
Roscovitine is a potent inhibitor of Cdk2/cyclin E (IC50: 0.1 ﾵM). It also inhibits Cdk7/cyclin H, Cdk5/p35, and Cdc2/cyclin B (IC50s: 0.49/0.16/0.65 ﾵM).
CAS nr:
186692-46-6
Purity:
98%
Molecular Weight:
354,45
SMILES:
CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1
Formula:
C19H26N6O
Pathway:
Cell Cycle/Checkpoint
Target:
CDK