Bioactivity:

Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active _-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF A_ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and

CAS nr:

1200493-78-2

Purity:

98%

Molecular Weight:

367,4

SMILES:

O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)SC=C3)=C2

Formula:

C18H14FN5OS

Pathway:

Neuroscience

Target:

BACE