Bioactivity:

GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).

CAS nr:

2215852-91-6

Purity:

98%

Molecular Weight:

485,41

SMILES:

FC1=C(C#N)C=CC(O[C@@H]2[C@@](CO)(O)CN(S(C3=C(C#N)C=C(C(F)(F)F)C=C3)(=O)=O)C2)=C1

Formula:

C20H15F4N3O5S

Pathway:

Membrane transporter/Ion channel

Target:

TRP/TRPV Channel