Bioactivity:

LLY-283 is an effective and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) (IC50: 22 nM and a Kd: 6 nM for PRMT5:MEP50 complex). It also shows antitumor activity.

CAS nr:

2040291-27-6

Purity:

98%

Molecular Weight:

342,35

SMILES:

O[C@H]1[C@@H](O[C@@]([C@@H](C2=CC=CC=C2)O)([H])[C@H]1O)N3C4=NC=NC(N)=C4C=C3

Formula:

C17H18N4O4

Pathway:

Others

Target:

Others