Bioactivity:

Antifolate C1 is an inhibitor of de novo purine biosynthesis. Antifolate C1 has selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter (PCFT) over the reduced folate carrier (RFC).

CAS nr:

136784-51-5

Purity:

98%

Molecular Weight:

447,46

SMILES:

O=C(O)[C@@H](NC(C1=CC=C(CCCC(N2)=CC3=C2N=C(N)NC3=O)S1)=O)CCC(O)=O

Formula:

C19H21N5O6S

Pathway:

Target: