Bioactivity:

PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110_, p110_, p110_, p110_, and VPS34, respectively.

CAS nr:

1276553-09-3

Purity:

98%

Molecular Weight:

380,4

SMILES:

FC1=C(C=CC(=C1)C#N)C1=C(SC(N2CCOCC2)=C1C#N)C1=NC=NN1

Formula:

C18H13FN6OS

Pathway:

PI3K/Akt/mTOR signaling,Apoptosis

Target:

PI3K,Apoptosis