Bioactivity:

CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukem

CAS nr:

292053-42-0

Purity:

98%

Molecular Weight:

332,33

SMILES:

COC(=O)C(\C#N)=C\c1ccc(o1)-c1ccc(cc1)S(N)(=O)=O

Formula:

C15H12N2O5S

Pathway:

Metabolism

Target:

Mitochondrial Metabolism