Bioactivity:

EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1_ and prevents its reoxidation.

CAS nr:

496807-64-8

Purity:

98%

Molecular Weight:

460,79

SMILES:

FC(F)(F)C1=NN(C2=CC(C(O)=O)=C(Cl)C=C2)C(/C1=C\C3=CC=C(C4=CC=CC=C4)O3)=O

Formula:

C22H12ClF3N2O4

Pathway:

Others

Target:

Others