Bioactivity:

Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.

CAS nr:

86377-53-9

Purity:

98%

Molecular Weight:

512,72

SMILES:

C[C@H](CC\C=C(/C)C(O)=O)C1C[C@H](OC(C)=O)[C@@]2(C)C3=CC[C@H]4C(C)(C)[C@H](O)CC[C@]4(C)C3=CC[C@]12C

Formula:

C32H48O5

Pathway:

Proteases/Proteasome,Apoptosis,MAPK,MAPK,Apoptosis,Apoptosis,MAPK,DNA Damage/DNA Repair

Target:

Caspase,Caspase,JNK,MAPK,Mdm2,p53,ERK,Topoisomerase