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Bioactivity:
GLPG1837 is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
CAS nr:
1654725-02-6
Purity:
98%
Molecular Weight:
348,42
SMILES:
CC1(C)Cc2c(sc(NC(=O)c3cc[nH]n3)c2C(N)=O)C(C)(C)O1
Formula:
C16H20N4O3S
Pathway:
Membrane transporter/Ion channel,Autophagy
Target:
CFTR,Autophagy