TargetMol Chemicals

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RO1138452 T4436

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

RO1138452 is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner.

CAS nr:

221529-58-4

Purity:

98%

Molecular Weight:

309,41

SMILES:

CC(C)Oc1ccc(Cc2ccc(NC3=NCCN3)cc2)cc1

Formula:

C19H23N3O

Pathway:

GPCR/G Protein,Immunology/Inflammation,Others

Target:

Prostaglandin Receptor,Prostaglandin Receptor,Others