Bioactivity:

Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.

CAS nr:

1374639-79-8

Purity:

98%

Molecular Weight:

570,64

SMILES:

O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.OC(CCC(O)=O)=O.[F,Cl,Br,I].O

Formula:

C27H38N8O6

Pathway:

Cell Cycle/Checkpoint

Target:

CDK