Bioactivity:

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).

CAS nr:

2113650-03-4

Purity:

98%

Molecular Weight:

594,7

SMILES:

CC1=CC(CN[C@H](CO)C(O)=O)=C(OCC2=CC(=CC=C2)C#N)C=C1OCC1=C(C)C(=CC=C1)C1=CC2=C(OCCO2)C=C1

Formula:

C35H34N2O7

Pathway:

Apoptosis,Immunology/Inflammation,Cell Cycle/Checkpoint

Target:

PD-1/PD-L1,PD-1/PD-L1,PD-1/PD-L1