Bioactivity:

Valecobulin hydrochloride (CKD-516 hydrochloride) is a valine prodrug of S516 and a vascular disrupting agent (VDA). It is a potent inhibitor of _-tubulin polymerization, and with marked antitumor activity against murine and human solid tumors.

CAS nr:

1240321-53-2

Purity:

98%

Molecular Weight:

573,06

SMILES:

CC(C)[C@H](N)C(NC1=NC(C2=CC=C(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)C(N4N=CN=C4)=C2)=CS1)=O.Cl

Formula:

C26H29ClN6O5S

Pathway:

Cytoskeletal Signaling

Target:

Microtubule Associated