Bioactivity:

LY2109761 is a novel selective TGF-_ receptor type I/II (T_RI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2.

CAS nr:

700874-71-1

Purity:

98%

Molecular Weight:

441,52

SMILES:

C(CN1CCOCC1)Oc1ccc2c(ccnc2c1)-c1c2CCCn2nc1-c1ccccn1

Formula:

C26H27N5O2

Pathway:

Stem Cells,Autophagy

Target:

TGF-beta/Smad,Autophagy