Quisinostat T6055
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Quisinostat (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs
CAS nr:
875320-29-9
Purity:
98%
Molecular Weight:
394,48
SMILES:
Cn1cc(c2ccccc12)CNCC1CCN(CC1)c1ncc(cn1)C(=O)NO
Formula:
C21H26N6O2
Pathway:
DNA Damage/DNA Repair,Chromatin/Epigenetic,Autophagy,Apoptosis
Target:
HDAC,HDAC,Autophagy,Apoptosis
