Bioactivity:

Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-_B transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit plate

CAS nr:

139051-27-7

Purity:

98%

Molecular Weight:

903,06

SMILES:

C[C@@H](CCC1=C(C)[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@@H]5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O1)CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Formula:

C45H74O18

Pathway:

MAPK,NF-_b,MAPK,Neuroscience,Immunology/Inflammation,Immunology/Inflammation

Target:

MEK,NF-_B,p38 MAPK,COX,COX,NO Synthase