Cyclopamine T2825
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Cyclopamine, a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.
CAS nr:
4449-51-8
Purity:
98%
Molecular Weight:
411,63
SMILES:
C[C@@H]1[C@@H]2NC[C@@H](C)C[C@H]2O[C@]11CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC2=C1C
Formula:
C27H41NO2
Pathway:
Stem Cells,Metabolism,GPCR/G Protein,Stem Cells
Target:
Smo,Endogenous Metabolite,Hedgehog/Smoothened,Hedgehog/Smoothened