Bioactivity:

Defactinib hydrochloride is a novel inhibitor of FAK which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

CAS nr:

1073160-26-5

Purity:

98%

Molecular Weight:

546,95

SMILES:

O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1.[H]Cl

Formula:

C20H22ClF3N8O3S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling

Target:

FAK,FAK,FAK