Bioactivity:

MS417 is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 _M.

CAS nr:

916489-36-6

Purity:

98%

Molecular Weight:

414,91

SMILES:

COC(=O)C[C@@H]1N=C(C2=C(SC(C)=C2C)N2C(C)=NN=C12)C1=CC=C(Cl)C=C1

Formula:

C20H19ClN4O2S

Pathway:

Microbiology/Virology,Proteases/Proteasome,Chromatin/Epigenetic

Target:

HIV Protease,HIV Protease,Epigenetic Reader Domain