Bioactivity:

AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 has the potential to treat asthma[1]. AZD9898 mitigates the GABA binding and hepatic toxicity signal.

CAS nr:

2042347-69-1

Purity:

98%

Molecular Weight:

457,83

SMILES:

O=C([C@@H]1[C@@H](C(C2=NC=C(N(C3=CC(Cl)=C(F)C=C3F)CC(C)(F)C)N=C2OC)=O)C1)O

Formula:

C20H19ClF3N3O4

Pathway:

Others

Target:

Others