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Bioactivity:
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).
CAS nr:
T8685
Purity:
98%
Molecular Weight:
453,47
SMILES:
Cn1cc(cn1)c2ccc5c(c2)ncnc5Nc4cccc(NC(=O)Nc3cccc(F)c3)c4
Formula:
C25H20FN7O
Pathway:
Chromatin/Epigenetic,Cell Cycle/Checkpoint
Target:
Aurora Kinase,Aurora Kinase