Bioactivity:

c-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM), shows superior antiproliferative activities against all the three GIST cell lines, GIST430, GIST882, and GIST48 (GI50s: 1, 3, and 2 nM).

CAS nr:

2121515-37-3

Purity:

98%

Molecular Weight:

519,62

SMILES:

CCN1CCN(C2=CC(NC3=NC=C(C4=CC=C(NC(NC5=NOC(CC)=C5)=O)C=C4)S3)=NC=N2)CC1

Formula:

C25H29N9O2S

Pathway:

Tyrosine Kinase/Adaptors

Target:

c-Kit