Bioactivity:

PF-5274857 is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor types including brain tumors and brain metastasis driven by

CAS nr:

1373615-35-0

Purity:

98%

Molecular Weight:

436,96

SMILES:

CC1=CC(=C(N=C1)C2=CC(=NC=C2Cl)N3CCN(CC3)C(=O)CCS(=O)(=O)C)C

Formula:

C20H25ClN4O3S

Pathway:

Stem Cells

Target:

Smo