Bioactivity:

DL-TBOA inhibited [14C] glutamate uptake in COS-1 cells expressing human EAAT1 and EAAT2, with Ki values of 42 _M and 5.7 _M, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner, with Ki values of 4.4 _M and 3.2 _M, respectively. DL-TBOA

CAS nr:

205309-81-5

Purity:

98%

Molecular Weight:

239,22

SMILES:

OC([C@@H](N)[C@@H](C(O)=O)OCC1=CC=CC=C1)=O.[Relative stereochemistry]

Formula:

C11H13NO5

Pathway:

Metabolism

Target:

transporter