Bioactivity:

Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-_-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/_-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100_nM) or transfected with a construct

CAS nr:

2247635-23-8

Purity:

98%

Molecular Weight:

1796,05

SMILES:

CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

Formula:

C83H114N18O23S2

Pathway:

Stem Cells,Cytoskeletal Signaling

Target:

Wnt/beta-catenin,Wnt/beta-catenin