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Bioactivity:
SB 203580 is a p38 MAPK inhibitor (IC50: 0.3-0.5 _M). It shows more than 100-fold selectivity over PKB, LCK, and GSK-3_.
CAS nr:
152121-47-6
Purity:
98%
Molecular Weight:
377,43
SMILES:
CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1
Formula:
C21H16FN3OS
Pathway:
MAPK,Autophagy,Autophagy
Target:
p38 MAPK,Autophagy,Mitophagy