Bioactivity:

BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.

CAS nr:

755038-02-9

Purity:

98%

Molecular Weight:

521,66

SMILES:

CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O

Formula:

C28H39N7O3

Pathway:

Cell Cycle/Checkpoint,Chromatin/Epigenetic,Apoptosis

Target:

PLK,Epigenetic Reader Domain,Apoptosis