Bioactivity:

MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 ﾵM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart fro

CAS nr:

1314883-11-8

Purity:

98%

Molecular Weight:

393,38

SMILES:

NC1=NC=C(C2=CC=C(S(=O)(C)=O)C=C2)C=C1C3=CC=C(C(F)(F)F)N=C3

Formula:

C18H14F3N3O2S

Pathway:

PI3K/Akt/mTOR signaling,Microbiology/Virology

Target:

PI4K,Parasite