Bioactivity:

TAK-441 is a potent inhibitor of the Hedgehog (Hh) signaling pathway. TAK-441 shows activity to suppress transcription factor Gli1 mRNA expression in tumor-associated stromal tissue and inhibited tumor growth (treatment/control ratio, 3%) in a mouse medul

CAS nr:

1186231-83-3

Purity:

98%

Molecular Weight:

576,56

SMILES:

O=C(C(N1C)=C(OCC(F)(F)F)C2=C1C=C(CC)N(CC(C3=CC=CC=C3)=O)C2=O)NC4CCN(C(CO)=O)CC4

Formula:

C28H31F3N4O6

Pathway:

Target: