Bioactivity:

Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 _M). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists

CAS nr:

870544-59-5

Purity:

98%

Molecular Weight:

445,42

SMILES:

CC(C)(C)C1=CC=CC=C1OC2=C(C=CC=N2)NC(=O)NC3=CC=C(C=C3)OC(F)(F)F

Formula:

C23H22F3N3O3

Pathway:

Neuroscience

Target:

P2 Receptor