Bioactivity:

Pralatrexate, (S)- is a folate analog dihydrofolate reductase (DHFR) inhibitor exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. Pralatrexate selectively enters cells expressing RFC-1; intr

CAS nr:

1320211-69-5

Purity:

98%

Molecular Weight:

477,48

SMILES:

O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C([C@H](CC2=NC3=C(N)N=C(N)N=C3N=C2)CC#C)C=C1)=O

Formula:

C23H23N7O5

Pathway:

Target: