Bioactivity:

AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.

CAS nr:

915720-21-7

Purity:

98%

Molecular Weight:

391,83

SMILES:

CC(C)Oc1n[nH]c(Nc(nc(N[C@@H](C)c(cc2)ncc2F)nc2)c2Cl)c1

Formula:

C17H19ClFN7O

Pathway:

Tyrosine Kinase/Adaptors

Target:

Trk receptor