SirReal1-O-propargyl T18641
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 _M. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2[1].
CAS nr:
1862237-99-7
Purity:
98%
Molecular Weight:
424,54
SMILES:
O=C(NC1=NC=C(CC2=CC=CC(OCC#C)=C2)S1)CSC3=NC(C)=CC(C)=N3
Formula:
C21H20N4O2S2
Pathway:
Others
Target:
Others
