Bioactivity:

LFM-A13_IC50=2.5 _M_, a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.

CAS nr:

244240-24-2

Purity:

98%

Molecular Weight:

360,01

SMILES:

C\C(O)=C(/C#N)C(=O)Nc1cc(Br)ccc1Br

Formula:

C11H8Br2N2O2

Pathway:

Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Angiogenesis,Tyrosine Kinase/Adaptors,Cell Cycle/Checkpoint

Target:

JAK,JAK,JAK,JAK,BTK,BTK,PLK