Bioactivity:

LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.

CAS nr:

1646321-63-2

Purity:

98%

Molecular Weight:

458,98

SMILES:

O=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1.[H]Cl

Formula:

C25H31ClN2O4

Pathway:

Immunology/Inflammation

Target:

Complement System