JR-AB2-011 T11728
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 _M). JR-AB2-011 has anti-glioblastoma multiforme (GBM) properties. JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 _M.
CAS nr:
329182-61-8
Purity:
98%
Molecular Weight:
398,28
SMILES:
CC1CN=C(S1)N(C(=O)Nc1ccc(Cl)c(Cl)c1)c1ccc(F)cc1
Formula:
C17H14Cl2FN3OS
Pathway:
PI3K/Akt/mTOR signaling
Target:
mTOR
