Bioactivity:

Nanaomycin A is the first selective DNMT3B inhibitor (IC50: 500 nM). Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum (IC80: 33.1 nM). Nanaomycin A is quinone antibiotics, reactivates silenced tumor suppressor gene

CAS nr:

52934-83-5

Purity:

>90%

Molecular Weight:

302,28

SMILES:

O=C(O)C[C@H]1CC(C(C2=C3C(O)=CC=C2)=O)=C(C3=O)[C@H](C)O1

Formula:

C16H14O6

Pathway:

Chromatin/Epigenetic,Microbiology/Virology,Metabolism

Target:

DNA Methyltransferase,Parasite,Dehydrogenase