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Bioactivity:
BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.
CAS nr:
2163056-91-3
Purity:
98%
Molecular Weight:
356,43
SMILES:
CN(C)C(=O)Cn1cc(cn1)-c1ccc(cc1)-c1cncc2ccccc12
Formula:
C22H20N4O
Pathway:
Cell Cycle/Checkpoint
Target:
CDK