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Bioactivity:
NB-360 is orally bioavailable and brain penetrable dual inhibitor of BACE1/BACE2 with IC50 of mouse and human BACE1=5 nM; BACE2=6 nM).
CAS nr:
1262857-73-7
Purity:
98%
Molecular Weight:
449,4
SMILES:
O=C(C1=NC=C(C#N)C=C1C)NC2=CC=C(F)C([C@]3(C)CO[C@](C(F)(F)F)(C)C(N)=N3)=C2
Formula:
C21H19F4N5O2
Pathway:
Neuroscience
Target:
BACE