Bioactivity:

Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03 _M. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 _M.

CAS nr:

1262888-28-7

Purity:

98%

Molecular Weight:

271,26

SMILES:

Fc1ccc(CNc2ncnc3c2cc(F)cc3)cc1

Formula:

C15H11F2N3

Pathway:

Ubiquitination,Cell Cycle/Checkpoint,DNA Damage/DNA Repair,Autophagy,Apoptosis

Target:

DUB,DUB,DUB,Autophagy,Apoptosis